Mesothelioma Immunostains
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Because of their specificity and sensitivity for mesotheliomas, the best combination appears to be calretinin and cytokeratin or WT for the positive markers and CEA and MOC or B., Ber EP, or BG for the negative markers..Invasion may be into visceral or parietal pleura or beyond and this can be highlighted with immunostains such as pancytokeratin or calretinin. Invasion by mesothelioma is often subtle and may be into only a few layers of collagenous tissue below the mesothelial space..
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