MRI shows potential to improve breast cancer risk prediction

breast cancer on mri MRI shows potential to improve breast cancer risk prediction
Breast Cancer

Among all cancers in ladies, he takes the initial place. In most cases, breast cancer develops within the presence of precancerous changes. This is primarily a benign mammary dysplasia and papilloma ducts.

Breast cancer is represented macroscopically nodular and diffuse forms, in addition to cancer with the nipple and also the nipple with the field (Paget's disease with the breast). For the nodular cancers are seen as the node having a diameter of up to several centimeters. In some cases, a tight knot, is permeated with whitish layers tissue penetrating into the surrounding dimply skin, in other people - a soft, juicy on the cut, splits easily. Diffuse prostate cancer is covered to get a considerable distance, the contours with the tumor are marked bad. Sometimes the cancer invades the skin and forms for the surface of decaying mushroom formation - a cancerous ulcer. In some cases, the tumor spreads across the surface from the breast and all the iron is included having a dense shell.

In histological structure are the following kinds of cancer of the breast:

• noninvasive: intralobular and intraduct;

• infiltrative.

Noninvasive breast cancers might be intralobular (lobular carcinoma in situ), and intraduct (ductal carcinoma in situ).

Infiltrating (invasive) cancer is characterized by varying levels of tissue and cell irregularities, which in a position to distinguish different amount of malignancy. This type of cancer include, in particular, infiltrating ductal and lobular carcinoma, which will has got the structure of scirrhus, in addition to Paget's disease.

Causes of Breast Cancer.

The causes of breast cancer often are hormonal changes inside the body: the entry into menopause, should there be an engaged restructuring in the hormonal regulation in the woman, the ovaries lose their activity, decreased manufacture of progesterone and estrogen, one's body will go through, "hormonal crisis." The mammary gland and endometrium (lining from the uterus) are most responsive to these changes, the breast type tissue actually starts to dissolve and turn into replaced by fat.

Scientifically established the female hormones estrogen-, plays an integral role inside the growth and development of breast cancers. The excess hormones inside the body generates a favorable background for developing the sickness. The least active hormones estrogen behave when pregnant and after birth - during breastfeeding. It is proved that this birth and prolonged breastfeeding (a lot more than one year) to relieve potential risk of developing breast cancer. On the other hand, abortion result in hormonal "explosion" inside a woman's body that can trigger the development of tumors. So far there is absolutely no consensus in regards to the impact for the progression of tumors of hormonal contraceptive drugs, yet it's considered that these drugs reduce the potential risk of developing breast cancer, but increase the potential risk of developing cancer of the female genital organs, and osteoporosis. In addition predisposition to cancer of the breast might cause harmful environmental factors: environmental surroundings, as well as inflammatory diseases previously deferred breast - mastitis.

In addition, patients using a group of first-degree relatives with cancer of the breast (mothers and sisters) likelihood of developing a tumor increasing by over half - familial kinds of cancer.

Benign breast diseases including fibrocystic breast disease, or fibroadenoz intraduct papillomatosis alone do not bring about cancer, but at the same time, create an unfavorable background for the development.

The source of breast cancer could be the results of radiation, including irradiation of the chest for other diseases (lung tumors, the lymphatic system), prolonged and frequent chest X-ray studies on inflammatory diseases or pulmonary tuberculosis.

Constitutional obesity can bring about cancer with the breast and female the reproductive system, having an excess fatty tissue inside the body, it will become an outside endocrine organ and actually starts to actively produce hormones-estrogens, whose action and provokes the growth and development of tumors.

Symptoms of Breast Cancer

There are many forms of the growth of breast cancer:

- Nodular form, the most typical, is characterized by a dense knot of 0.5 to five cm or higher, it can be characterized by all from the following symptoms;

- Diffuse. All of them are very aggressive, grow quickly, almost lightning speed, the tumor with no clear boundaries, "spreading" in the breast and skin. For the first 2 forms are characteristic signs of inflammation: pain of the breast, a bright red colorization from the skin it raises temperature to 39 degrees C. In view of those symptoms often occur, and errors in diagnosis of patients treated for inflammatory diseases, that happen to be named and are described these forms breast cancer. When tubular carcinoma breast cancer cover like a "skin" of its contracting and decreasing in space.

In some cases, cancer of the breast manifests inside the form of metastases in the lymph nodes for the affected side, often doesn't detect the tumor itself - show hidden cancer of the breast.

For small tumors of the breast, any symptoms arise. The most observant as well as their husbands can detect tumor site inside the gland accidentally, but in the large breast to detect small size hard knot. Revealed a knot can be painful when pressed, round, smooth and agile, this speaks and only a benign tumor. Signs of malignancy other: a strong knot to touch the stone, its surface is uneven, it's stationary or slightly shifted, may be firmly fixed for the surrounding tissue or skin, usually painless, can reach a significant size (greater than three to five cm and infrequently 10-15 cm).

Need to assess the surface in the skin within the tumor: the malignant process will probably be observed retraction with the skin, collecting within the folds, wrinkles, a signal of "lemon peel" - a neighborhood swelling of the skin in the tumor, is often a direct tumor invasion to the skin surface, then it is a bright red color and sprawl as "cauliflower."

Share this post