Penn Vet Research Overview

breast cancer on dogs Penn Vet Research Overview
Breast Cancer

Among all cancers in women, he takes consumers. In most cases, breast cancer develops inside presence of precancerous changes. This is primarily a benign mammary dysplasia and papilloma ducts.

Breast cancer is represented macroscopically nodular and diffuse forms, in addition to cancer in the nipple and the nipple in the field (Paget's disease from the breast). For the nodular cancers are seen as the node developing a diameter as high as several centimeters. In certain instances, a strong knot, is permeated with whitish layers tissue penetrating to the surrounding fat, on other occasions - a soft, juicy about the cut, splits easily. Diffuse cancer of prostate is covered to get a considerable distance, the contours of the tumor are marked bad. Sometimes the cancer invades your skin layer and forms on the surface of decaying mushroom formation - a cancerous ulcer. In some cases, the tumor spreads down the surface in the breast and the iron is covered with a dense shell.

In histological structure would be the following varieties of cancer of the breast:

• noninvasive: intralobular and intraduct;

• infiltrative.

Noninvasive cancer of the breast may be intralobular (lobular carcinoma in situ), and intraduct (ductal carcinoma in situ).

Infiltrating (invasive) cancer is seen as varying examples of tissue and cell irregularities, which permitted to distinguish different degree of malignancy. This type of cancer include, especially, infiltrating ductal and lobular carcinoma, which will has the structure of scirrhus, as well as Paget's disease.

Causes of Breast Cancer.

The factors behind breast cancer often are hormonal changes within the body: the entry into menopause, if you have an active restructuring with the hormonal regulation of the woman, the ovaries lose their activity, decreased production of progesterone and estrogen, one's body goes through, "hormonal crisis." The mammary gland and endometrium (lining in the uterus) are most understanding of these changes, the breast growth begins to dissolve and become replaced by fat.

Scientifically established the female hormones estrogen-, plays a vital role in the development of breast cancer. The excess hormones in the body produces a favorable background for developing the sickness. The least active hormones estrogen behave during pregnancy and after birth - during breastfeeding. It is proved that this birth and prolonged breastfeeding (a lot more than 12 months) to lessen the risk of developing breast cancers. On the other hand, abortion bring about hormonal "explosion" in a very woman's body that can trigger the growth and development of tumors. So far there isn't any consensus in regards to the impact about the continuing development of tumors of hormonal contraceptive drugs, however it is belief that these drugs reduce the potential risk of developing breast cancers, but increase the chance of developing cancer of the female genital organs, and osteoporosis. In addition predisposition to breast cancer could cause harmful environmental factors: the planet, and also inflammatory diseases previously deferred breast - mastitis.

In addition, patients with a category of first-degree relatives with breast cancers (mothers and sisters) chance of creating a tumor increasing by more than half - familial types of cancer.

Benign breast diseases like fibrocystic breast disease, or fibroadenoz intraduct papillomatosis alone usually do not result in cancer, but concurrently, create an unfavorable background for the development.

The reason for breast cancer may be the outcomes of radiation, like irradiation with the chest for other diseases (lung tumors, the lymphatic system), prolonged and frequent chest X-ray studies on inflammatory diseases or pulmonary tuberculosis.

Constitutional obesity can cause cancer with the breast and female reproductive system, with the excess fatty tissue inside the body, it will become another endocrine organ and begins to actively produce hormones-estrogens, whose action and provokes the continuing development of tumors.

Symptoms of Breast Cancer

There are some forms in the growth of breast cancer:

- Nodular form, the most typical, is seen as a a dense knot of 0.5 to five cm or more, it's seen as all in the following symptoms;

- Diffuse. All of them are very aggressive, grow quickly, almost lightning speed, the tumor without having clear boundaries, "spreading" with the breast and skin. For the first two forms are characteristic indications of inflammation: pain with the breast, a bright red color of the skin it raises body's temperature to 39 degrees C. In view of these symptoms often occur, and errors in proper diagnosis of patients treated for inflammatory diseases, which can be named and are described these forms breast cancers. When tubular carcinoma cancer of the breast cover like a "skin" of its contracting and decreasing in proportions.

In certain cases, breast cancers manifests inside form of metastases within the lymph nodes for the affected side, often fails to detect the tumor itself - show hidden breast cancer.

For small tumors of the breast, any symptoms arise. The most observant females and their husbands can easily detect tumor site in the gland unintentionally, but in a very large breast to detect small size hard knot. Revealed a knot can be painful when pressed, round, smooth and agile, this speaks in support of a benign tumor. Signs of malignancy other: a strong knot to touch the stone, its surface is uneven, it can be stationary or slightly shifted, can be firmly fixed towards the surrounding tissue or skin, usually painless, can reach a tremendous size (more than three to five cm and often 10-15 cm).

Need to assess the surface with the skin over the tumor: the malignant process will probably be observed retraction of the skin, obtaining inside folds, wrinkles, an indicator of "lemon peel" - an area swelling from the skin within the tumor, is often a direct tumor invasion to your skin surface, then it might be a bright red color and sprawl as "cauliflower."

Share this post