MRI Improves Breast Cancer Screening in Older BRCA Carriers Cancer Network

breast cancer on mri MRI Improves Breast Cancer Screening in Older BRCA Carriers Cancer Network
Breast Cancer

Among all cancers in females, he takes the ultimate place. In most cases, breast cancers develops in the presence of precancerous changes. This is primarily a benign mammary dysplasia and papilloma ducts.

Breast cancer is represented macroscopically nodular and diffuse forms, and also cancer from the nipple and the nipple of the field (Paget's disease of the breast). For the nodular cancers are seen as an the node developing a diameter all the way to several centimeters. In some instances, a strong knot, is permeated with whitish layers tissue penetrating into the surrounding fat, on other occasions - a soft, juicy about the cut, splits easily. Diffuse prostate cancer is included to get a considerable distance, the contours with the tumor are marked bad. Sometimes the cancer invades the skin and forms about the surface of decaying mushroom formation - a cancerous ulcer. In certain cases, the tumor spreads across the surface in the breast and all the iron is included which has a dense shell.

In histological structure are the following varieties of breast cancers:

• noninvasive: intralobular and intraduct;

• infiltrative.

Noninvasive breast cancer may be intralobular (lobular carcinoma in situ), and intraduct (ductal carcinoma in situ).

Infiltrating (invasive) cancer is characterized by varying examples of tissue and cell irregularities, which allowed to distinguish different a higher level malignancy. This type of cancer include, especially, infiltrating ductal and lobular carcinoma, which often has got the structure of scirrhus, as well as Paget's disease.

Causes of Breast Cancer.

The causes of breast cancer often are hormonal changes in the body: the entry into menopause, should there be an energetic restructuring in the hormonal regulation from the woman, the ovaries lose their activity, decreased production of progesterone and estrogen, our bodies goes through, "hormonal crisis." The mammary gland and endometrium (lining from the uterus) are most understanding of these changes, the breast type tissue starts to dissolve and become replaced by fat.

Scientifically established the female hormones estrogen-, plays an important role inside the continuing development of breast cancer. The excess hormones inside body produces a favorable background for developing the disease. The least active hormones estrogen behave in pregnancy and after birth - during breastfeeding. It is proved how the birth and prolonged breastfeeding (more than twelve months) to relieve the potential risk of developing cancer of the breast. On the other hand, abortion lead to hormonal "explosion" in a very woman's body that may trigger the progression of tumors. So far there isn't any consensus concerning the impact on the growth and development of tumors of hormonal contraceptive drugs, but it is considered that these drugs reduce the potential risk of developing breast cancer, but increase the risk of developing cancer with the female genital organs, and osteoporosis. In addition predisposition to breast cancers may cause harmful environmental factors: the planet, in addition to inflammatory diseases previously deferred breast - mastitis.

In addition, patients which has a group of first-degree relatives with breast cancer (mothers and sisters) chance of having a tumor increasing by greater than half - familial forms of cancer.

Benign breast diseases for example fibrocystic breast disease, or fibroadenoz intraduct papillomatosis alone usually do not cause cancer, but at the same time, create an unfavorable background due to the development.

The cause of cancer of the breast will be the outcomes of radiation, for example irradiation from the chest for other diseases (lung tumors, the lymphatic system), prolonged and frequent chest X-ray studies on inflammatory diseases or pulmonary tuberculosis.

Constitutional obesity can lead to cancer in the breast and female the reproductive system, with the excess dimply skin in the body, it might be another endocrine organ and actually starts to actively produce hormones-estrogens, whose action and provokes the growth and development of tumors.

Symptoms of Breast Cancer

There are a couple of forms in the growth of cancer of the breast:

- Nodular form, the commonest, is characterized by a dense knot of 0.5 to five cm or more, it can be seen as an all in the following symptoms;

- Diffuse. All of them are very aggressive, grow quickly, almost lightning speed, the tumor without clear boundaries, "spreading" in the breast and skin. For the first 2 forms are characteristic signs of inflammation: pain from the breast, a bright beautiful red colors of the skin it raises body's temperature to 39 degrees C. In view of the symptoms often occur, and errors in diagnosing patients treated for inflammatory diseases, which are named and they are known as these forms breast cancer. When tubular carcinoma cancer of the breast cover being a "skin" of the contracting and decreasing in space.

In certain instances, breast cancers manifests inside the form of metastases within the lymph nodes on the affected side, often doesn't detect the tumor itself - show hidden breast cancers.

For small tumors in the breast, any symptoms arise. The most observant females and their husbands are able to detect tumor site within the gland unintentionally, but in a large breast to detect small size hard knot. Revealed a knot could be painful when pressed, round, smooth and agile, this speaks and only a benign tumor. Signs of malignancy other: a good knot to touch the stone, its surface is uneven, it is stationary or slightly shifted, may be firmly fixed on the surrounding tissue or skin, usually painless, can reach a significant size (over three to five cm and infrequently 10-15 cm).

Need to assess the surface of the skin over the tumor: the malignant process will likely be observed retraction in the skin, collecting within the folds, wrinkles, a signal of "lemon peel" - a local swelling of the skin on the tumor, is often a direct tumor invasion to the skin surface, then it will become a bright red colorization and sprawl as "cauliflower."

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