MRI tumor features help predict breast cancer recurrence

breast cancer on mri MRI tumor features help predict breast cancer recurrence
Breast Cancer

Among all cancers in females, he takes the first place. In most cases, breast cancer develops in the presence of precancerous changes. This is primarily a benign mammary dysplasia and papilloma ducts.

Breast cancer is represented macroscopically nodular and diffuse forms, along with cancer from the nipple along with the nipple from the field (Paget's disease with the breast). For the nodular cancers are seen as an the node using a diameter up to several centimeters. In some instances, a good knot, is permeated with whitish layers tissue penetrating to the surrounding dimply skin, in other people - a soft, juicy for the cut, splits easily. Diffuse cancer of the prostate is roofed for any considerable distance, the contours from the tumor are marked bad. Sometimes the cancer invades skin and forms around the surface of decaying mushroom formation - a cancerous ulcer. In certain instances, the tumor spreads over the surface from the breast and all sorts of the iron is roofed with a dense shell.

In histological structure are the following varieties of breast cancer:

• noninvasive: intralobular and intraduct;

• infiltrative.

Noninvasive cancer of the breast might be intralobular (lobular carcinoma in situ), and intraduct (ductal carcinoma in situ).

Infiltrating (invasive) cancer is seen as an varying degrees of tissue and cell irregularities, which in a position to distinguish different level of malignancy. This type of cancer include, particularly, infiltrating ductal and lobular carcinoma, which in turn gets the structure of scirrhus, as well as Paget's disease.

Causes of Breast Cancer.

The causes of breast cancer often are hormonal changes within the body: the entry into menopause, if you have a dynamic restructuring of the hormonal regulation of the woman, the ovaries lose their activity, decreased creation of progesterone and estrogen, the body goes through, "hormonal crisis." The mammary gland and endometrium (lining in the uterus) are most understanding of these changes, the breast tissue starts to dissolve and stay replaced by fat.

Scientifically established the female hormones estrogen-, plays a key role in the development of cancer of the breast. The excess hormones inside body produces a favorable background for developing the sickness. The least active hormones estrogen behave when pregnant and after birth - during breastfeeding. It is proved that this birth and prolonged breastfeeding (a lot more than one year) to relieve the potential risk of developing breast cancer. On the other hand, abortion lead to hormonal "explosion" inside a woman's body that will trigger the continuing development of tumors. So far there's no consensus concerning the impact for the continuing development of tumors of hormonal contraceptive drugs, but it is thought that these drugs reduce the potential risk of developing cancer of the breast, but increase the potential risk of developing cancer of the female genital organs, and osteoporosis. In addition predisposition to cancer of the breast may cause harmful environmental factors: the surroundings, and also inflammatory diseases previously deferred breast - mastitis.

In addition, patients which has a category of first-degree relatives with breast cancer (mothers and sisters) likelihood of creating a tumor increasing by a lot more than half - familial forms of cancer.

Benign breast diseases for example fibrocystic breast disease, or fibroadenoz intraduct papillomatosis alone don't cause cancer, but at the same time, create an unfavorable background because of its development.

The cause of cancer of the breast would be the outcomes of radiation, for example irradiation in the chest for other diseases (lung tumors, the lymphatic system), prolonged and frequent chest X-ray studies on inflammatory diseases or pulmonary tuberculosis.

Constitutional obesity can bring about cancer in the breast and female reproductive system, having an excess fatty tissue in the body, it will become a separate endocrine organ and actually starts to actively produce hormones-estrogens, whose action and provokes the continuing development of tumors.

Symptoms of Breast Cancer

There are several forms of the growth of breast cancers:

- Nodular form, the most typical, is seen as an a dense knot of 0.5 to five cm or higher, it is seen as a all with the following symptoms;

- Diffuse. All of them are very aggressive, grow quickly, almost lightning speed, the tumor without any clear boundaries, "spreading" with the breast and skin. For the first two forms are characteristic indications of inflammation: pain from the breast, a bright red colorization in the skin it raises temperature to 39 degrees C. In view of those symptoms often occur, and errors in diagnosing patients treated for inflammatory diseases, that happen to be named and they are described these forms breast cancer. When tubular carcinoma cancer of the breast cover like a "skin" of the contracting and decreasing in dimensions.

In certain cases, cancer of the breast manifests inside the form of metastases within the lymph nodes around the affected side, often ceases to detect the tumor itself - show hidden breast cancers.

For small tumors with the breast, any symptoms arise. The most observant women and their husbands are able to detect tumor site within the gland accidentally, but in a very large breast to detect small size hard knot. Revealed a knot may be painful when pressed, round, smooth and agile, this speaks and only a benign tumor. Signs of malignancy other: a decent knot to touch the stone, its surface is uneven, it can be stationary or slightly shifted, could be firmly fixed towards the surrounding tissue or skin, usually painless, can reach a tremendous size (over 3 - 5 cm and often 10-15 cm).

Need to evaluate the surface in the skin on the tumor: the malignant process is going to be observed retraction of the skin, collecting inside folds, wrinkles, a symptom of "lemon peel" - an area swelling of the skin within the tumor, might be a direct tumor invasion to skin surface, then it becomes a bright red colorization and sprawl as "cauliflower."

Share this post