FDA Requests More Volunteers For Male Breast Cancer Research, Hopes To Boost Awareness About Disease

breast cancer on male FDA Requests More Volunteers For Male Breast Cancer Research, Hopes To Boost Awareness About Disease
Breast Cancer

Among all cancers in women, he takes the ultimate place. In most cases, breast cancer develops inside the presence of precancerous changes. This is primarily a benign mammary dysplasia and papilloma ducts.

Breast cancer is represented macroscopically nodular and diffuse forms, in addition to cancer with the nipple and the nipple in the field (Paget's disease in the breast). For the nodular cancers are characterized by the node creating a diameter as high as several centimeters. In some instances, a good knot, is permeated with whitish layers tissue penetrating to the surrounding dimply skin, in others - a soft, juicy for the cut, splits easily. Diffuse cancer of prostate is roofed for a considerable distance, the contours with the tumor are marked bad. Sometimes the cancer invades your skin and forms on the surface of decaying mushroom formation - a cancerous ulcer. In certain cases, the tumor spreads along the surface in the breast and many types of the iron is roofed having a dense shell.

In histological structure would be the following types of cancer of the breast:

• noninvasive: intralobular and intraduct;

• infiltrative.

Noninvasive breast cancer could be intralobular (lobular carcinoma in situ), and intraduct (ductal carcinoma in situ).

Infiltrating (invasive) cancer is seen as an varying levels of tissue and cell irregularities, which allowed to distinguish different a higher level malignancy. This type of cancer include, specifically, infiltrating ductal and lobular carcinoma, which in turn gets the structure of scirrhus, as well as Paget's disease.

Causes of Breast Cancer.

The causes of cancer of the breast often are hormonal changes inside body: the entry into menopause, should there be an active restructuring of the hormonal regulation of the woman, the ovaries lose their activity, decreased creation of progesterone and estrogen, our bodies is certainly going through, "hormonal crisis." The mammary gland and endometrium (lining from the uterus) are most tuned in to these changes, the breast tissue starts to dissolve and stay replaced by fat.

Scientifically established that this female hormones estrogen-, plays a vital role inside the continuing development of cancer of the breast. The excess hormones within the body results in a favorable background for developing the disease. The least active hormones estrogen behave when pregnant and after birth - during breastfeeding. It is proved that this birth and prolonged breastfeeding (greater than twelve months) to cut back the potential risk of developing breast cancers. On the other hand, abortion cause hormonal "explosion" in a woman's body that could trigger the growth and development of tumors. So far there is absolutely no consensus regarding the impact for the growth and development of tumors of hormonal contraceptive drugs, but it's thought that these drugs reduce the chance of developing cancer of the breast, but increase potential risk of developing cancer of the female genital organs, and osteoporosis. In addition predisposition to breast cancers may cause harmful environmental factors: the environment, in addition to inflammatory diseases previously deferred breast - mastitis.

In addition, patients which has a group of first-degree relatives with cancer of the breast (mothers and sisters) probability of making a tumor increasing by greater than half - familial types of cancer.

Benign breast diseases for example fibrocystic breast disease, or fibroadenoz intraduct papillomatosis alone do not result in cancer, but at the same time, create an unfavorable background for the development.

The reason behind breast cancers will be the results of radiation, for example irradiation of the chest for other diseases (lung tumors, the lymphatic system), prolonged and frequent chest X-ray studies on inflammatory diseases or pulmonary tuberculosis.

Constitutional obesity can cause cancer from the breast and female reproductive system, with the excess fat inside body, it is another endocrine organ and actually starts to actively produce hormones-estrogens, whose action and provokes the growth and development of tumors.

Symptoms of Breast Cancer

There are many forms of the growth of breast cancer:

- Nodular form, the commonest, is seen as an a dense knot of 0.5 to 5 cm or even more, it's seen as a all from the following symptoms;

- Diffuse. All of them are very aggressive, grow quickly, almost lightning speed, the tumor without any clear boundaries, "spreading" in the breast and skin. For the initial two forms are characteristic warning signs of inflammation: pain of the breast, a bright red colorization from the skin it raises body temperature to 39 degrees C. In view of these symptoms often occur, and errors in diagnosis of patients treated for inflammatory diseases, that happen to be named and they are described these forms cancer of the breast. When tubular carcinoma breast cancer cover as a "skin" of the contracting and decreasing in proportions.

In certain instances, breast cancers manifests inside form of metastases within the lymph nodes on the affected side, often doesn't detect the tumor itself - show hidden breast cancer.

For small tumors with the breast, any symptoms arise. The most observant women and their husbands are able to detect tumor site within the gland unintentionally, but in a large breast to detect small size hard knot. Revealed a knot may be painful when pressed, round, smooth and agile, this speaks in support of a benign tumor. Signs of malignancy other: a good knot to touch the stone, its surface is uneven, it is stationary or slightly shifted, can be firmly fixed towards the surrounding tissue or skin, usually painless, can reach an important size (over 3 - 5 cm and often 10-15 cm).

Need to assess the surface of the skin within the tumor: the malignant process will be observed retraction with the skin, obtaining within the folds, wrinkles, an indication of "lemon peel" - an area swelling in the skin on the tumor, is often a direct tumor invasion to skin surface, then it might be a bright red color and sprawl as "cauliflower."

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