MRI Shows Potential to Improve Breast Cancer Risk Prediction

breast cancer on mri MRI Shows Potential to Improve Breast Cancer Risk Prediction
Breast Cancer

Among all cancers in women, he takes the first place. In most cases, breast cancers develops inside the presence of precancerous changes. This is primarily a benign mammary dysplasia and papilloma ducts.

Breast cancer is represented macroscopically nodular and diffuse forms, along with cancer in the nipple as well as the nipple with the field (Paget's disease with the breast). For the nodular cancers are seen as the node having a diameter of up to several centimeters. In certain instances, a strong knot, is permeated with whitish layers tissue penetrating in to the surrounding fat, in other people - a soft, juicy around the cut, splits easily. Diffuse cancer of the prostate is covered for the considerable distance, the contours from the tumor are marked bad. Sometimes the cancer invades your skin layer and forms on the surface of decaying mushroom formation - a cancerous ulcer. In some cases, the tumor spreads over the surface in the breast and all the iron is roofed using a dense shell.

In histological structure are the following kinds of breast cancers:

• noninvasive: intralobular and intraduct;

• infiltrative.

Noninvasive breast cancer might be intralobular (lobular carcinoma in situ), and intraduct (ductal carcinoma in situ).

Infiltrating (invasive) cancer is seen as varying levels of tissue and cell irregularities, which able to distinguish different degree of malignancy. This type of cancer include, in particular, infiltrating ductal and lobular carcinoma, which often has the structure of scirrhus, and also Paget's disease.

Causes of Breast Cancer.

The causes of breast cancers often are hormonal changes within the body: the entry into menopause, should there be an engaged restructuring with the hormonal regulation with the woman, the ovaries lose their activity, decreased creation of progesterone and estrogen, one's body goes through, "hormonal crisis." The mammary gland and endometrium (lining in the uterus) are most tuned in to these changes, the breast growth begins to dissolve and become replaced by fat.

Scientifically established the female hormones estrogen-, plays a key role within the development of cancer of the breast. The excess hormones in the body produces a favorable background for developing the sickness. The least active hormones estrogen behave during pregnancy and after birth - during breastfeeding. It is proved that this birth and prolonged breastfeeding (over 1 year) to lessen the risk of developing cancer of the breast. On the other hand, abortion lead to hormonal "explosion" in a woman's body that can trigger the continuing development of tumors. So far there is no consensus regarding the impact for the development of tumors of hormonal contraceptive drugs, but it is thought that these drugs reduce the chance of developing cancer of the breast, but increase potential risk of developing cancer from the female genital organs, and osteoporosis. In addition predisposition to breast cancers may cause harmful environmental factors: the environment, in addition to inflammatory diseases previously deferred breast - mastitis.

In addition, patients which has a family of first-degree relatives with cancer of the breast (mothers and sisters) likelihood of having a tumor increasing by more than half - familial varieties of cancer.

Benign breast diseases such as fibrocystic breast disease, or fibroadenoz intraduct papillomatosis alone tend not to cause cancer, but as well, create an unfavorable background due to the development.

The cause of breast cancers may be the results of radiation, such as irradiation in the chest for other diseases (lung tumors, the lymphatic system), prolonged and frequent chest X-ray studies on inflammatory diseases or pulmonary tuberculosis.

Constitutional obesity can bring about cancer of the breast and female reproductive :, by having an excess dimply skin within the body, it becomes an outside endocrine organ and starts to actively produce hormones-estrogens, whose action and provokes the development of tumors.

Symptoms of Breast Cancer

There are several forms in the growth of cancer of the breast:

- Nodular form, the most frequent, is seen as a dense knot of 0.5 to five cm or even more, it is seen as a all from the following symptoms;

- Diffuse. All of them are very aggressive, grow quickly, almost lightning speed, the tumor without having clear boundaries, "spreading" with the breast and skin. For the initial two forms are characteristic warning signs of inflammation: pain from the breast, a bright red color of the skin it raises temperature to 39 degrees C. In view of those symptoms often occur, and errors in diagnosis of patients treated for inflammatory diseases, that happen to be named and are known these forms breast cancers. When tubular carcinoma cancer of the breast cover being a "skin" of its contracting and decreasing in proportions.

In some cases, cancer of the breast manifests inside form of metastases within the lymph nodes on the affected side, often fails to detect the tumor itself - show hidden breast cancer.

For small tumors in the breast, any symptoms arise. The most observant as well as their husbands have the ability to detect tumor site in the gland accidentally, but in the large breast to detect small size hard knot. Revealed a knot might be painful when pressed, round, smooth and agile, this speaks in favor of a benign tumor. Signs of malignancy other: a tight knot to touch the stone, its surface is uneven, it is stationary or slightly shifted, might be firmly fixed towards the surrounding tissue or skin, usually painless, can reach an important size (more than 3 - 5 cm and infrequently 10-15 cm).

Need to gauge the surface with the skin in the tumor: the malignant process will probably be observed retraction with the skin, collecting inside the folds, wrinkles, a signal of "lemon peel" - a neighborhood swelling in the skin on the tumor, might be a direct tumor invasion to skin surface, then it will become a bright beautiful red colors and sprawl as "cauliflower."

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